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The information in this section is intended for Healthcare Professionals only.

US residents should consult the EMD Serono, Inc. for information on products approved for sales in the United States of America.

Ovidrel/Ovitrelle®
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Ovidrel®/Ovitrelle® (choriogonadotropin alfa) is the world's first recombinant liquid prefilled chorionic gonadotropin (r-hCG) for the treatment of anovulation, or absence of ovulation, the most common cause of infertility in women. Anovulation is brought about by irregularities in the hormones needed to produce and release healthy eggs.

Ovidrel®/Ovitrelle® is administered after the stimulation of the growth of follicles (or eggs) by follicle stimulating hormone (FSH). It is used to trigger ovulation in women with anovulation and to promote final maturation of eggs in the ovaries of women undergoing assisted reproductive technologies (ART) such as in-vitro fertilization.

Ovidrel®/Ovitrelle® is produced by recombinant DNA technology and delivered in a liquid, prefilled syringe.

        The role of hCG in the body
        The primary role of human chorionic gonadotropin (hCG) in vivo is to maintain the corpus luteum (hormone-secreting body formed at the site of ovulation) which secrets estrogen and progesterone, the two hormones necessary to support the first trimester of pregnancy. Ovidrel®/Ovitrelle® is a recombinant chorionic gonadotropin, which is equivalent in its structure to the naturally occurring hCG in the body. However, as hCG can act very similarly to LH, Ovidrel®/Ovitrelle® is used in clinical practice to complete the maturation of the oocyte.
              Last updated: 05/12/2007